Sperm oxidative stress: clinical significance and management

Oxidative stress is one of the leading causes sperm dysfunction. Excessive amounts reactive oxygen species can damage membranes and disrupt their DNA integrity, which affects not only likelihood getting pregnant naturally, but also clinical outcomes assisted reproductive technologies risk miscarriage. Sperm cells are extremely vulnerable to oxidative stress, given limited functional reserve antioxidant systems repair apparatus. Lifestyle factors, most modifiable, often trigger generation species. Both lifestyle modification use dietary supplements adequate compatible ways combat male stress-associated infertility. The search for other internal external sources species, identification etiology treatment respective diseases necessary successful regulation redox processes in system practice, required overcome infertility, prevent induced epigenetic disorders subsequent generations. article presents analysis molecular mechanisms idiopathic authors provide an overview how as subfebrile fever. provides modern therapeutics, well options eliminating consequences effect on spermatogenesis general.